Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803380 | 0.89 | CALM1 (0.51) | ALOX15CALM1MEN1KMT2ADRD2 | |
| SCHEMBL10697670 | 0.84 | CALM1 (0.50) | ALOX15CALM1MEN1KMT2ADRD2 | |
| SCHEMBL8062950 | 0.84 | ALOX15 (0.60) | ALOX15ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL8805151 | 0.79 | DRD2 (0.53) | CALM1DRD2DRD4DRD3TAAR1 | |
| SCHEMBL6056697 | 0.79 | ALOX15 (0.58) | ALOX15ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL8077879 | 0.78 | ALOX15 (0.56) | ALOX15ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL8076317 | 0.78 | ALOX15 (0.56) | ALOX15ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL8076016 | 0.78 | ALOX15 (0.56) | ALOX15ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL8076536 | 0.78 | ALOX15 (0.56) | ALOX15ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL10686363 | 0.75 | ALDH1A1 (0.50) | ALDH1A1CALM1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0150892-B1 | SUBSTITUTED ALKYLIDENE IMIDAZOLES | G.D. Searle & Co. (US) | 1991-04-24 | — | — | EP | disclosed |
| US-4837333-A | SELECTIVE INHIBITOR OF THROMBOXANE SYNTHETASE ENZYME | G. D. SEARLE & CO. (US) | 1989-06-06 | — | — | US | disclosed |