Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.50 |
| ▸ | IGF1R | P08069 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8803380 | 0.95 | CALM1 (0.51) | CALM1IGF1RALOX15MEN1KMT2A | |
| SCHEMBL8805151 | 0.88 | DRD2 (0.53) | CALM1TAAR1SIGMAR1DRD2DRD4 | |
| SCHEMBL10686363 | 0.86 | ALDH1A1 (0.50) | CALM1TAAR1DRD2DRD4DRD3 | |
| SCHEMBL10686361 | 0.86 | ALDH1A1 (0.50) | CALM1TAAR1DRD2DRD4DRD3 | |
| SCHEMBL9827273 | 0.84 | ALOX15 (0.44) | CALM1IGF1RALOX15MEN1KMT2A | |
| SCHEMBL18230822 | 0.83 | PKM (0.61) | CALM1IGF1RALOX15MEN1KMT2A | |
| SCHEMBL14277958 | 0.81 | PPARA (0.42) | CALM1IGF1RALOX15TAAR1SIGMAR1 | |
| SCHEMBL4254058 | 0.80 | CALM1 (0.72) | CALM1IGF1RALOX15TAAR1SIGMAR1 | |
| SCHEMBL8482733 | 0.80 | SMN1; SMN2 (0.53) | CALM1IGF1RALOX15MEN1KMT2A | |
| SCHEMBL8802834 | 0.79 | MEN1 (0.45) | MEN1KMT2ASIGMAR1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0267439-A2 | Alpha-(phenylalkyl) pyridinealkanol derivatives | G.D. Searle & Co. (US) | 1988-05-18 | — | — | EP | disclosed |