Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.60 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.56 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.53 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9149818 | 0.93 | TMEM97 (0.59) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL7037787 | 0.90 | LMNA (0.62) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL3570124 | 0.90 | LMNA (0.65) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL9053101 | 0.89 | LMNA (0.66) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL17448248 | 0.86 | RAB9A (0.68) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL9826975 | 0.85 | SIGMAR1 (0.70) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL14066867 | 0.83 | HDAC1 (0.63) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL4337942 | 0.83 | MAPT (0.55) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL7915502 | 0.83 | TMEM97 (0.60) | RAB9ASMN1; SMN2NPC1MAPTLMNA | |
| SCHEMBL9628232 | 0.83 | KCNH2 (0.76) | SIGMAR1KCNH2TSHRATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0285284-B1 | N-PHENETHYLAMINOALKYL-BENZAMIDE ANTI-ARRHYTHMIA AGENTS | Pfizer Limited (GB) | 1991-05-15 | — | — | EP | disclosed |