Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19874839 | 0.89 | KMT2A (0.58) | KMT2ARAB9AMEN1MAPTRXFP1 | |
| SCHEMBL11876573 | 0.83 | MAPT (0.50) | KMT2ARAB9AMEN1MAPTRXFP1 | |
| SCHEMBL4083653 | 0.82 | ALDH1A1 (0.50) | RAB9AMAPTLMNAMAPK1HPGD | |
| SCHEMBL1656800 | 0.81 | HPGD (0.56) | KMT2ARAB9AMEN1MAPTRXFP1 | |
| SCHEMBL9828649 | 0.80 | KMT2A (0.53) | KMT2ARAB9AMEN1MAPTKDM4E | |
| SCHEMBL1873600 | 0.79 | HSD17B14 (0.49) | KMT2AMEN1RXFP1MAPK1GAA | |
| SCHEMBL10796499 | 0.79 | CNR2 (0.55) | RXFP1MAPK1HPGDCES2CES1 | |
| SCHEMBL26988861 | 0.78 | MAPT (0.51) | KMT2ARAB9AMEN1MAPTRXFP1 | |
| SCHEMBL960010 | 0.77 | ALDH1A1 (0.51) | KMT2AMAPTLMNAGAAKDM4E | |
| SCHEMBL20412776 | 0.76 | RAB9A (0.54) | KMT2ARAB9AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249950-B1 | AROMATIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-06-19 | — | — | EP | disclosed |
| EP-0085959-B1 | AROMATIC COMPOUNDS | THE WELLCOME FOUNDATION LIMITED (GB) | 1989-04-19 | — | — | EP | disclosed |
| EP-0249950-A1 | Aromatic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-12-23 | — | — | EP | disclosed |
| EP-0085959-A2 | Aromatic compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1983-08-17 | — | — | EP | disclosed |