Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 7/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | LSS | P48449 | 2/20 | 0.43 |
| ▸ | CHKA | P35790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10680303 | 0.83 | CA2 (0.66) | CHRNA7CA1CA2CA12CA9 | |
| SCHEMBL8343036 | 0.82 | CA1 (0.63) | CA1CA2CA12CA9KDM4E | |
| SCHEMBL9827177 | 0.82 | TP53 (0.46) | TP53KDM4EALDH1A1LMNALSS | |
| SCHEMBL9828388 | 0.80 | CHKA (0.48) | TP53KDM4EALDH1A1LMNACHKA | |
| SCHEMBL9827139 | 0.77 | POLB (0.54) | ALDH1A1LMNA | |
| SCHEMBL9828313 | 0.77 | JAK2 (0.47) | TP53ALDH1A1LMNACHKA | |
| SCHEMBL9827723 | 0.76 | CHRNA7 (0.48) | CHRNA7CA1CA2CA12CA9 | |
| SCHEMBL8323422 | 0.76 | CA2 (0.52) | CHRNA7CA1CA2CA12CA9 | |
| SCHEMBL9828971 | 0.74 | CA2 (0.42) | CHRNA7CA1CA2CA12CA9 | |
| SCHEMBL16966466 | 0.73 | ALDH1A1 (0.62) | CA1CA2CA12CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0291210-B1 | ANTIARRHYTHMIC AGENTS | Pfizer Limited (GB) | 1991-11-06 | — | — | EP | disclosed |
| US-4835165-A | Antiarrhythmic 4-phenylpiperidines | PFIZER INC. (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0291210-A1 | Antiarrhythmic agents | Pfizer Limited (GB) | 1988-11-17 | — | — | EP | disclosed |