Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.51 |
| ▸ | PAM | P19021 | 2/20 | 0.51 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828212 | 1.00 | DGKA (0.51) | DGKAPAMCES2PRSS1PRSS2 | |
| SCHEMBL9828285 | 0.96 | PAM (0.49) | DGKAPAMCES2PRSS1PRSS2 | |
| SCHEMBL9828213 | 0.91 | PAM (0.61) | DGKAPAMPRSS1PRSS2PRSS3 | |
| SCHEMBL9828168 | 0.91 | PAM (0.61) | DGKAPAMPRSS1PRSS2PRSS3 | |
| SCHEMBL9829208 | 0.87 | PAM (0.50) | DGKAPAMPRSS1PRSS2PRSS3 | |
| SCHEMBL9828308 | 0.87 | PAM (0.50) | DGKAPAMPRSS1PRSS2PRSS3 | |
| SCHEMBL9829213 | 0.87 | PAM (0.50) | DGKAPAMPRSS1PRSS2PRSS3 | |
| SCHEMBL9828848 | 0.87 | CES2 (0.50) | DGKAPAMCES2TSHRMAPT | |
| SCHEMBL9829386 | 0.85 | PAM (0.48) | DGKAPAMCES2PRSS1PRSS2 | |
| SCHEMBL9828306 | 0.81 | ACHE (0.50) | CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0247201-B1 | PROPANE-1,3-DIOL DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1991-05-15 | — | — | EP | disclosed |
| US-4945098-A | Novel propane-1,3-diol derivatives and use | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1990-07-31 | — | — | US | disclosed |
| EP-0247201-A1 | PROPANE-1,3-DIOL DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION. | LEO PHARM PROD LTD (DK) | 1987-12-02 | — | — | EP | disclosed |
| WO-1987003281-A1 | PROPANE-1,3-DIOL DERIVATIVES, A METHOD FOR THEIR PRODUCTION AND A PHARMACEUTICAL COMPOSITION | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 1987-06-04 | — | — | WO | disclosed |