Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030084 | 0.82 | LMNA (0.42) | CA2CA5AKDM4EPOLBGAA | |
| SCHEMBL7143494 | 0.78 | CA2 (0.40) | CA2CA5AKDM4EPOLBGAA | |
| SCHEMBL9837136 | 0.78 | KDM4E (0.34) | CA2CA5AKDM4EPOLBGAA | |
| SCHEMBL2900297 | 0.77 | LMNA (0.60) | KDM4EPOLBGAATDP1LMNA | |
| SCHEMBL4340762 | 0.77 | TSHR (0.59) | KDM4EPOLBGAALMNAMAPT | |
| SCHEMBL2468681 | 0.76 | CA12 (0.41) | CA2CA5AKDM4EPOLBGAA | |
| SCHEMBL4338296 | 0.74 | MRGPRX4 (0.52) | CA2CA5AKDM4ELMNAMAPT | |
| SCHEMBL809274 | 0.73 | KMT2A (0.55) | KDM4EPOLBGAACA12CA9 | |
| SCHEMBL465132 | 0.72 | LMNA (0.52) | POLBGAATDP1LMNAMAPT | |
| SCHEMBL9202118 | 0.71 | LMNA (0.45) | CA2CA5APOLBGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0197294-B1 | BETA-LACTAM ANTIBIOTICS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | BAYER AG (DE) | 1991-04-03 | — | — | EP | disclosed |
| EP-0197294-A2 | Beta-lactam antibiotics, process for their preparation and their use as medicaments | BAYER AG (DE) | 1986-10-15 | — | — | EP | disclosed |