Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9828429 | 0.78 | CA2 (0.41) | KDM4EKMT2AMAOAMAOBGAA | |
| SCHEMBL7030084 | 0.69 | LMNA (0.42) | KDM4EKMT2AMAOAMAOBGAA | |
| SCHEMBL5515460 | 0.67 | ALDH1A1 (0.42) | KDM4ETDP1HSD17B10 | |
| SCHEMBL4338296 | 0.66 | MRGPRX4 (0.52) | KDM4EKMT2AALOX15CA2CA5A | |
| SCHEMBL7143494 | 0.66 | CA2 (0.40) | KDM4EKMT2AMAOAMAOBSMN1; SMN2 | |
| SCHEMBL809274 | 0.65 | KMT2A (0.55) | KDM4EKMT2ASMN1; SMN2GAALMNA | |
| SCHEMBL4340762 | 0.65 | TSHR (0.59) | KDM4EKMT2AMAOAMAOBALOX15 | |
| SCHEMBL2900297 | 0.65 | LMNA (0.60) | KDM4EKMT2AMAOBALOX15SMN1; SMN2 | |
| SCHEMBL465132 | 0.64 | LMNA (0.52) | KMT2ASMN1; SMN2GAALMNATDP1 | |
| SCHEMBL3155781 | 0.64 | EIF2AK2 (0.68) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253235-B1 | 1,8-BRIDGED 4-QUINOLONE CARBOXYLIC ACIDS AND MEDICAMENTS CONTANING THEM | BAYER AG (DE) | 1991-01-02 | — | — | EP | disclosed |
| EP-0187315-A2 | Basic quinolonecarboxylic-acid preparations | BAYER AG (DE) | 1986-07-16 | — | — | EP | disclosed |