Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 11/20 | 0.50 |
| ▸ | ITGAV | P06756 | 4/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5085780 | 1.00 | CTSB (0.53) | CTSBITGB3ITGAVCTSKCTSL | |
| SCHEMBL29542801 | 0.88 | ITGB3 (0.50) | ITGB3ITGAVCTSKCTSLCTSS | |
| SCHEMBL2928358 | 0.88 | ITGB3 (0.50) | ITGB3ITGAVCTSKCTSLCTSS | |
| SCHEMBL4121793 | 0.88 | ITGB3 (0.50) | ITGB3ITGAVCTSKCTSLCTSS | |
| SCHEMBL2185240 | 0.87 | ITGB3 (0.58) | ITGB3CTSKCTSLCTSSITGB1 | |
| SCHEMBL844471 | 0.87 | ITGB3 (0.58) | ITGB3CTSKCTSLCTSSITGB1 | |
| SCHEMBL7758997 | 0.87 | ITGB3 (0.58) | ITGB3CTSKCTSLCTSSITGB1 | |
| SCHEMBL5085119 | 0.87 | CTSK (0.50) | ITGB3ITGAVCTSKCTSSITGA2B | |
| SCHEMBL5500451 | 0.87 | CTSL (0.50) | ITGB3ITGAVCTSLITGA2BACE | |
| SCHEMBL4682778 | 0.87 | ITGB3 (0.47) | ITGB3ITGAVCTSKITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |