Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 19/20 | 0.48 |
| ▸ | PYGM | P11217 | 19/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10968852 | 0.91 | PYGM (0.37) | PYGLPYGM | |
| SCHEMBL10649530 | 0.90 | PYGL (0.39) | PYGLPYGM | |
| SCHEMBL10967987 | 0.89 | ALDH1A1 (0.44) | PYGLPYGM | |
| SCHEMBL9827653 | 0.87 | PYGM (0.35) | PYGLPYGM | |
| SCHEMBL10969370 | 0.87 | PYGM (0.35) | PYGLPYGM | |
| SCHEMBL30157261 | 0.86 | PYGM (0.62) | PYGLPYGMALOX15 | |
| SCHEMBL4072118 | 0.86 | PYGM (0.62) | PYGLPYGMALOX15 | |
| SCHEMBL9828158 | 0.85 | PYGM (0.35) | PYGLPYGM | |
| SCHEMBL10374293 | 0.83 | PYGM (0.49) | PYGLPYGM | |
| SCHEMBL10687926 | 0.82 | PYGM (0.48) | PYGLPYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0235347-B1 | DIHYDROPYRIDINE LACTOLS, PROCESSES FOR THEIR PREPARATION, AND THEIR USE AS PHARMACEUTICAL COMPOUNDS | BAYER AG (DE) | 1991-10-09 | — | — | EP | disclosed |
| EP-0258729-B1 | DIHYDROPYRIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | BAYER AG (DE) | 1990-04-25 | — | — | EP | disclosed |
| EP-0235347-A2 | Dihydropyridine lactols, processes for their preparation, and their use as pharmaceutical compounds | BAYER AG (DE) | 1987-09-09 | — | — | EP | disclosed |