SCHEMBL30157261

SCHEMBL30157261

CCN1C(C)=C(C(=O)OC(C)C)C(c2ccccc2Cl)C2=C1COC2=O

nearest known ligand 0.62

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PYGM P11217 19/20 0.62
PYGL P06737 18/20 0.62
ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4072118 1.00 PYGM (0.62) PYGMPYGLALOX15
SCHEMBL9865950 0.91 PYGM (0.52) PYGMPYGL
SCHEMBL9864934 0.90 PYGM (0.49) PYGMPYGL
SCHEMBL9865516 0.89 PYGL (0.48) PYGMPYGL
SCHEMBL9867642 0.87 PYGL (0.46) PYGMPYGL
SCHEMBL9865794 0.86 PYGM (0.46) PYGMPYGL
SCHEMBL10425160 0.86 PYGM (0.46) PYGMPYGLALOX15
SCHEMBL9829022 0.86 PYGL (0.48) PYGMPYGLALOX15
SCHEMBL10659301 0.86 PYGL (0.52) PYGMPYGL
SCHEMBL9865957 0.84 PYGL (0.44) PYGMPYGL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4561704-A2 USE OF GLYCOGEN METABOLISM INHIBITORS FOR THE TREATMENT OF CANCER The University Of Vermont (US) 2025-06-04 EP claimed
WO-2024026458-A2 USE OF GLYCOGEN METABOLISM INHIBITORS FOR THE TREATMENT OF CANCER THE UNIVERSITY OF VERMONT (US) 2024-02-01 WO claimed
EP-4110344-A2 USE OF THYROMIMETICS FOR THE TREATMENT OF CANCER The University Of Vermont (US) 2023-01-04 EP claimed
EP-4561704-A2 USE OF GLYCOGEN METABOLISM INHIBITORS FOR THE TREATMENT OF CANCER The University Of Vermont (US) 2025-06-04 EP disclosed
WO-2024026458-A2 USE OF GLYCOGEN METABOLISM INHIBITORS FOR THE TREATMENT OF CANCER THE UNIVERSITY OF VERMONT (US) 2024-02-01 WO disclosed
EP-4110344-A2 USE OF THYROMIMETICS FOR THE TREATMENT OF CANCER The University Of Vermont (US) 2023-01-04 EP disclosed