Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30327418 | 0.82 | TSHR (0.35) | LMNATSHRALOX12ACHE | |
| SCHEMBL6694446 | 0.78 | LMNA (0.32) | LMNATSHRALOX12ACHE | |
| SCHEMBL5085715 | 0.74 | — | — | |
| SCHEMBL538790 | 0.67 | LMNA (0.40) | LMNATSHRALOX12ACHE | |
| SCHEMBL335200 | 0.67 | — | — | |
| SCHEMBL135100 | 0.67 | ACHE (0.40) | LMNATSHRALOX12ACHE | |
| SCHEMBL31614548 | 0.66 | ACHE (0.33) | ACHE | |
| SCHEMBL6911968 | 0.66 | ACHE (0.33) | ACHE | |
| SCHEMBL30973629 | 0.66 | — | — | |
| Biphenyl SCHEMBL936183 | 0.65 | ALDH1A1 (0.69) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200408-B1 | INHIBITORS OF 5-LIPOXYGENASE | Pfizer Corporation (PA) | 1991-11-13 | — | — | EP | disclosed |
| US-4694080-A | LIPOXYGENASE INHIBITORS, BRONCHODILATOR, AND ANTIALLERGENS | PFIZER INC. (US) | 1987-09-15 | — | — | US | disclosed |
| EP-0200408-A1 | Inhibitors of 5-lipoxygenase | Pfizer Corporation (PA) | 1986-11-05 | — | — | EP | disclosed |
| US-4179511-A | Antibacterial 3-(5-tetrazolyl) penam compounds | PFIZER INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-4143039-A | ANTIBACTERIAL 3-(5-TETRAZOLYL)PENAM COMPOUNDS | PFIZER INC. (US) | 1979-03-06 | — | — | US | disclosed |
| US-4136096-A | REACTING A 3-CYANO-PENAM WITH AN AZIDE | PFIZER INC. (US) | 1979-01-23 | — | — | US | disclosed |
| US-4115385-A | PENICILLINS | PFIZER INC. (US) | 1978-09-19 | — | — | US | disclosed |
| US-4105668-A | 6-AMINO-2,2-DIMETHYL-3-(1 -SUBSTITUTED TETRAZOL-5-YL)PENAM COMPOUND REACTED WITH HYDROGEN FLUORIDE | PFIZER INC. (US) | 1978-08-08 | — | — | US | disclosed |
| US-4081455-A | ANTIBACTERIAL | PFIZER INC. (US) | 1978-03-28 | — | — | US | disclosed |
| US-3994939-A | BACTERICIDES | PFIZER INC. (US) | 1976-11-30 | — | — | US | disclosed |
| US-3992394-A | PENICILLIN INTERMEDIATES FOR BACTERICIDES | PFIZER INC. (US) | 1976-11-16 | — | — | US | disclosed |