Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 10/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829242 | 0.86 | ADORA3 (0.60) | MEN1KMT2AMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL9830542 | 0.84 | ALDH1A1 (0.66) | MEN1KMT2AALDH1A1HSD17B10POLB | |
| SCHEMBL9829548 | 0.84 | MEN1 (0.59) | MEN1KMT2AALDH1A1POLBRAB9A | |
| SCHEMBL9829907 | 0.82 | LMNA (0.59) | MEN1KMT2AMAPK1ALDH1A1HSD17B10 | |
| SCHEMBL9830897 | 0.82 | MAPT (0.56) | MEN1KMT2AMAPK1ALDH1A1POLB | |
| SCHEMBL9829872 | 0.82 | RAB9A (0.62) | MEN1KMT2AALDH1A1RAB9ANPC1 | |
| SCHEMBL9832583 | 0.80 | LMNA (0.57) | MEN1KMT2AMAPK1ALDH1A1ALOX15 | |
| SCHEMBL9831892 | 0.80 | ABL1 (0.60) | MEN1KMT2AMAPK1ALDH1A1RAB9A | |
| SCHEMBL9829808 | 0.80 | RAB9A (0.58) | MEN1KMT2AMAPK1ALOX15HSD17B10 | |
| SCHEMBL18029531 | 0.80 | MEN1 (1.00) | MEN1KMT2AMAPK1ALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |