Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831892 | 0.88 | ABL1 (0.60) | LMNASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL9832583 | 0.88 | LMNA (0.57) | LMNASMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL9829808 | 0.88 | RAB9A (0.58) | LMNANPC1RAB9AMAPTHTT | |
| SCHEMBL9829548 | 0.87 | MEN1 (0.59) | LMNASMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL9829242 | 0.87 | ADORA3 (0.60) | LMNASMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL9831121 | 0.85 | GSTO1 (0.58) | LMNASMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL9831484 | 0.84 | MEN1 (0.64) | LMNASMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL9829872 | 0.83 | RAB9A (0.62) | SMN1; SMN2KDM4ENPC1RAB9AMAPT | |
| SCHEMBL9829752 | 0.82 | MEN1 (0.65) | LMNAKDM4ENPC1RAB9AMAPT | |
| SCHEMBL9831311 | 0.81 | LMNA (0.60) | LMNASMN1; SMN2KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |