Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.41 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829904 | 1.00 | NAAA (0.50) | NAAANOD1TP53SMN1; SMN2PADI1 | |
| SCHEMBL10482744 | 0.95 | NOD1 (0.45) | NAAANOD1TP53LMNACA2 | |
| SCHEMBL17026719 | 0.94 | NAAA (0.55) | NAAANOD1TP53SMN1; SMN2CPB2 | |
| SCHEMBL25046028 | 0.92 | TP53 (0.50) | NAAANOD1TP53LMNACA2 | |
| SCHEMBL1951843 | 0.92 | TP53 (0.50) | NAAANOD1TP53LMNACA2 | |
| SCHEMBL1951845 | 0.92 | TP53 (0.50) | NAAANOD1TP53LMNACA2 | |
| SCHEMBL9829322 | 0.90 | NAAA (0.45) | NAAASMN1; SMN2PADI1PADI4LMNA | |
| SCHEMBL9829324 | 0.90 | NAAA (0.45) | NAAASMN1; SMN2PADI1PADI4LMNA | |
| SCHEMBL10669986 | 0.89 | LMNA (0.43) | NAAATP53SMN1; SMN2PADI1PADI4 | |
| SCHEMBL10669991 | 0.89 | LMNA (0.43) | NAAATP53SMN1; SMN2PADI1PADI4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |