Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832363 | 0.89 | OPRM1 (0.43) | CYP1A2CYP3A4CYP2D6CYP2C9ALDH1A1 | |
| SCHEMBL9831654 | 0.88 | MAPT (0.41) | CYP3A4KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9799267 | 0.82 | CYP3A4 (0.46) | CYP1A2CYP3A4CYP2D6BLMPMP22 | |
| SCHEMBL11389394 | 0.81 | OPRM1 (0.51) | CYP1A2CYP3A4CYP2D6BLMPMP22 | |
| SCHEMBL9799289 | 0.76 | OPRM1 (0.43) | CYP1A2CYP3A4CYP2D6CYP2C9KDM4E | |
| SCHEMBL9799232 | 0.73 | OPRM1 (0.40) | CYP1A2CYP3A4CYP2D6CYP2C9ALDH1A1 | |
| SCHEMBL10423292 | 0.72 | KDM4E (0.41) | KDM4EGAA | |
| SCHEMBL9834283 | 0.70 | OPRM1 (0.58) | CYP3A4KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL9832805 | 0.70 | OPRM1 (0.70) | CYP3A4CYP2D6PMP22KDM4EALDH1A1 | |
| Fedotozine SCHEMBL154629 | 0.69 | OPRM1 (0.63) | CYP3A4KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297782-B1 | A THIOPHENE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1991-05-22 | — | — | EP | claimed |