Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799232 | 0.90 | OPRM1 (0.40) | MAPTPTGS2TUBB4ATUBBTUBA3C | |
| SCHEMBL9799267 | 0.88 | CYP3A4 (0.46) | KDM4ECHRM2ADRA2BSLC6A4OPRM1 | |
| SCHEMBL9831654 | 0.82 | MAPT (0.41) | KDM4EGAAMAPTAKR1B1ALOX5 | |
| SCHEMBL9832269 | 0.81 | MAPT (0.36) | KDM4EGAAMAPTALOX5PTGS1 | |
| SCHEMBL9799280 | 0.80 | SIGMAR1 (0.40) | CHRM2SLC6A4OPRM1SLC6A3KCNH2 | |
| SCHEMBL9799293 | 0.76 | FDPS (0.38) | MAPTKCNH2 | |
| SCHEMBL9834283 | 0.76 | OPRM1 (0.58) | KDM4EGAAMAPTALOX5PTGS1 | |
| SCHEMBL9799289 | 0.75 | OPRM1 (0.43) | KDM4EGAAMAPTPTGS2TUBB4A | |
| SCHEMBL9832363 | 0.72 | OPRM1 (0.43) | MAPTPTGS2TUBB4ATUBBTUBA3C | |
| SCHEMBL9830311 | 0.72 | CYP1A2 (0.40) | KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4946862-A | Thiophene derivative and process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |