Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1194033 | 0.78 | RAB9A (0.80) | HTR2BSMN1; SMN2RAB9ACASP3SENP8 | |
| SCHEMBL9830414 | 0.77 | ATP4A (0.44) | SMN1; SMN2RAB9ACASP3SENP8SENP7 | |
| SCHEMBL2048608 | 0.77 | HTR2B (0.57) | HTR2BSMN1; SMN2RAB9ACASP3SENP8 | |
| SCHEMBL10512375 | 0.77 | CYP19A1 (0.44) | HTR2BRAB9ACYP19A1ALDH1A1ALOX15 | |
| SCHEMBL9830320 | 0.76 | HTR2C (0.45) | CYP19A1ALDH1A1ALOX15TSHRMAPT | |
| SCHEMBL3180259 | 0.75 | HTR2B (0.50) | HTR2BSMN1; SMN2RAB9AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL888552 | 0.75 | CYP19A1 (0.43) | HTR2BRAB9ACYP19A1ALDH1A1ALOX15 | |
| Pulicatins F SCHEMBL12469099 | 0.75 | HTR2B (1.00) | HTR2BSMN1; SMN2RAB9ACASP3SENP8 | |
| SCHEMBL15423067 | 0.75 | HTR2B (0.71) | HTR2BSMN1; SMN2RAB9ACASP3SENP8 | |
| SCHEMBL21883091 | 0.74 | HTR2B (0.54) | HTR2BSMN1; SMN2RAB9ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |