SCHEMBL21883091

SCHEMBL21883091

OCc1csc(-c2ccccc2O)n1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2B P41595 4/20 0.54
ALDH1A1 P00352 3/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
RAB9A P51151 2/20 0.50
CASP3 P42574 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
CYP19A1 P11511 1/20 0.47
NUDT1 P36639 1/20 0.46
PIM1 P11309 4/20 0.43
SREBF2 Q12772 1/20 0.43
KDM4E B2RXH2 2/20 0.43
GAA P10253 1/20 0.43
ATM Q13315 1/20 0.43
HPGD P15428 1/20 0.41
BCL2L1 Q07817 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15356487 0.82 MPL (0.50) ALDH1A1L3MBTL1TDP1RAB9ASMN1; SMN2
SCHEMBL6415273 0.81 ALDH1A1 (0.46) ALDH1A1L3MBTL1TDP1RAB9ASMN1; SMN2
SCHEMBL5895082 0.81 ALDH1A1 (0.73) ALDH1A1L3MBTL1TDP1RAB9ASMN1; SMN2
SCHEMBL4727339 0.81 ALDH1A1 (0.46) ALDH1A1L3MBTL1TDP1SMN1; SMN2NUDT1
SCHEMBL8847516 0.80 KDM4E (0.58) HTR2BALDH1A1L3MBTL1TDP1RAB9A
SCHEMBL104951 0.78 KDM4E (0.58) ALDH1A1L3MBTL1RAB9ASMN1; SMN2KDM4E
SCHEMBL15356484 0.77 SHMT2 (0.57) ALDH1A1TDP1RAB9ACYP19A1PIM1
SCHEMBL1194033 0.76 RAB9A (0.80) HTR2BALDH1A1RAB9ACASP3SMN1; SMN2
SCHEMBL3047990 0.75 HTR2B (0.49) HTR2BALDH1A1L3MBTL1TDP1RAB9A
SCHEMBL9830640 0.74 HTR2B (0.60) HTR2BALDH1A1L3MBTL1TDP1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250319017-A1 OPEN-CELL FOAM BASED WOUND TREATMENT SMITH SCOTT C (US) 2025-10-16 US claimed
EP-4531940-A1 OPEN-CELL FOAM BASED WOUND TREATMENT Smith, Scott C. (US) 2025-04-09 EP claimed
EP-4216966-B1 FORMULATION BASED ON POLYHEXAMETHYLENE BIGUANIDE FOR USE IN THE TREATMENT OF ACANTHAMOEBA KERATITIS AND/OR FUNGAL INFECTIONS SIFI SPA (IT) 2024-11-13 EP claimed
WO-2023230285-A1 OPEN-CELL FOAM BASED WOUND TREATMENT SMITH SCOTT C (US) 2023-11-30 WO claimed
WO-2026090608-A2 PEPTIDE COMPOUNDS FOR TRAUMATIC BRAIN INJURY The Government of the United States, as represented by the Director of the Defense Health Agency (US) 2026-04-30 WO disclosed
US-20260021159-A1 STABLE PEPTIDE COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATMENT OF MODERATE/SEVERE DRY EYE-RELATED OCULAR SYMPTOMS TEARSOLUTIONS INC (US) 2026-01-22 US disclosed
US-20260001997-A1 SULFUR POLYMER IDAHO STATE UNIV (US) 2026-01-01 US disclosed
US-20250319017-A1 OPEN-CELL FOAM BASED WOUND TREATMENT SMITH SCOTT C (US) 2025-10-16 US disclosed
US-20250222070-A1 STABLE PEPTIDE COMPOSITIONS TEARSOLUTIONS INC (US) 2025-07-10 US disclosed
EP-4326353-B1 ENHANCED ANTIMICROBIAL EFFICACY (SYNERGY) OF SILVER AND COPPER COMPOUNDS AND MEDICAL USE OF THEIR COMBINATIONS NANORDICA MEDICAL OUE (EE) 2025-06-18 EP disclosed
EP-4547221-A2 STABLE PEPTIDE COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATMENT OF MODERATE/SEVERE DRY EYE-RELATED OCULAR SYMPTOMS TearSolutions, Inc. (US) 2025-05-07 EP disclosed
EP-4531940-A1 OPEN-CELL FOAM BASED WOUND TREATMENT Smith, Scott C. (US) 2025-04-09 EP disclosed
CN-115650409-A Photocatalysis-biological coupling denitrification and denitrification system and in-situ construction method thereof 中国科学技术大学苏州高等研究院 2023-01-31 CN disclosed
EP-4095152-A2 ENGINEERED RIBOSOMAL PROMOTERS FOR PROTEIN PRODUCTION IN MICROORGANISMS Danisco US Inc. (US) 2022-11-30 EP disclosed
EP-3419991-B1 ENGINEERED RIBOSOMAL PROMOTERS FOR PROTEIN PRODUCTION IN MICROORGANISMS DANISCO US INC (US) 2022-10-26 EP disclosed
US-20220305083-A1 STABLE PEPTIDE COMPOSITIONS TEARSOLUTIONS INC (US) 2022-09-29 US disclosed
US-11447782-B2 Engineered ribosomal promoters for protein production in microorganisms DANISCO US INC. (US) 2022-09-20 US disclosed
EP-3986914-A1 CONSTRAINED PEPTIDES TearSolutions, Inc. (US) 2022-04-27 EP disclosed
US-20220105167-A1 ESCHERICHIA COLI 0157:H7 PROTEINS AND USES THEREOF Institut National de Recherche pour l'Agriculture, l'Alimentation et I'Environnement (FR) 2022-04-07 US disclosed
EP-3632919-A1 IMIDAZOTHIADIAZOLE AND IMIDAZOPYRAZINE DERIVATIVES AS PROTEASE ACTIVATED RECEPTOR 4 (PAR4) INHIBITORS FOR TREATING PLATELET AGGREGATION Bristol-Myers Squibb Company (US) 2020-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260021159-A1 STABLE PEPTIDE COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATMENT OF MODERATE/SEVERE DRY EYE-RELATED OCULAR SYMPTOMS TRPC1, TRPC7, ASNS HTR2B 2632/4885ALDH1A1 4599/4885L3MBTL1 2028/4885
US-20260001997-A1 SULFUR POLYMER STS, TST, CBS HTR2B 1082/4885ALDH1A1 884/4885L3MBTL1 3159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.