Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830728 | 1.00 | PPARG (0.52) | PPARGPPARAITGB1ITGA4ITGB3 | |
| SCHEMBL9830731 | 0.88 | CA2 (0.54) | PPARGITGB1ITGB3ITGA2BTAS1R3 | |
| SCHEMBL9830744 | 0.88 | CA2 (0.54) | PPARGITGB1ITGB3ITGA2BTAS1R3 | |
| SCHEMBL9828758 | 0.84 | PIN1 (0.43) | LMNASMN1; SMN2GPR132HPGD | |
| SCHEMBL9828763 | 0.84 | PIN1 (0.43) | LMNASMN1; SMN2GPR132HPGD | |
| SCHEMBL7300949 | 0.83 | ITGB3 (0.41) | ITGB1ITGA4ITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL7300962 | 0.83 | ITGB3 (0.41) | ITGB1ITGA4ITGB3ITGA2BSMN1; SMN2 | |
| SCHEMBL1310658 | 0.82 | ACE (0.48) | ITGB1ITGB3ITGA2BITGAVITGA5 | |
| SCHEMBL1310656 | 0.82 | ACE (0.48) | ITGB1ITGB3ITGA2BITGAVITGA5 | |
| SCHEMBL11273089 | 0.82 | CA2 (0.52) | GPR132RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |