Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 4/20 | 0.54 |
| ▸ | NPY4R | P50391 | 4/20 | 0.54 |
| ▸ | NPY1R | P25929 | 3/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 13/20 | 0.54 |
| ▸ | MMP3 | P08254 | 3/20 | 0.54 |
| ▸ | MMP9 | P14780 | 2/20 | 0.54 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 3/20 | 0.51 |
| ▸ | MMP7 | P09237 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832852 | 0.93 | MMP1 (0.56) | NPY5RNPY4RNPY1RNPY2RMMP1 | |
| SCHEMBL9830988 | 0.85 | MMP1 (0.56) | MMP1 | |
| SCHEMBL24276096 | 0.79 | ITGB3 (0.59) | — | |
| SCHEMBL23974227 | 0.79 | ITGB3 (0.59) | — | |
| SCHEMBL7442999 | 0.78 | PSMB5 (0.60) | NPY5RNPY4RNPY1RNPY2RMMP1 | |
| SCHEMBL17741125 | 0.78 | PSMB5 (0.60) | NPY5RNPY4RNPY1RNPY2RMMP1 | |
| SCHEMBL5558887 | 0.77 | MMP2 (0.75) | MMP1MMP3MMP9ADAM17MMP2 | |
| SCHEMBL7359195 | 0.77 | ECE1 (0.44) | NPY5RNPY4RNPY1RNPY2RMMP1 | |
| SCHEMBL28221966 | 0.77 | MMP1 (0.60) | MMP1MMP3MMP9ADAM17MMP2 | |
| SCHEMBL28221962 | 0.77 | MMP1 (0.60) | MMP1MMP3MMP9ADAM17MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258289-A4 | PEPTIDE ANALOGS | — | 1991-01-02 | — | — | EP | disclosed |
| EP-0258289-A1 | PEPTIDE ANALOGS | ABBOTT LABORATORIES (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004349-A1 | PEPTIDE ANALOGS | DELLARIA JOSEPH | 1987-07-30 | — | — | WO | disclosed |