Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 12/20 | 0.56 |
| ▸ | MMP3 | P08254 | 3/20 | 0.56 |
| ▸ | MMP2 | P08253 | 3/20 | 0.56 |
| ▸ | MMP9 | P14780 | 2/20 | 0.56 |
| ▸ | NPY4R | P50391 | 4/20 | 0.55 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.55 |
| ▸ | NPY1R | P25929 | 3/20 | 0.55 |
| ▸ | NPY2R | P49146 | 1/20 | 0.55 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.55 |
| ▸ | MMP7 | P09237 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830801 | 0.93 | NPY5R (0.54) | MMP1MMP3MMP2MMP9NPY4R | |
| SCHEMBL7442999 | 0.86 | PSMB5 (0.60) | MMP1MMP3MMP2NPY4RNPY5R | |
| SCHEMBL5558798 | 0.82 | MMP1 (0.74) | MMP1MMP3MMP2MMP9ADAM17 | |
| SCHEMBL17741125 | 0.81 | PSMB5 (0.60) | MMP1NPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL24276096 | 0.80 | ITGB3 (0.59) | PTPN1 | |
| SCHEMBL23974227 | 0.80 | ITGB3 (0.59) | PTPN1 | |
| SCHEMBL9830988 | 0.80 | MMP1 (0.56) | MMP1 | |
| SCHEMBL25627830 | 0.79 | REN (0.57) | MMP1MMP3MMP9NPY4RNPY5R | |
| SCHEMBL25627640 | 0.79 | REN (0.57) | MMP1MMP3MMP9NPY4RNPY5R | |
| SCHEMBL5558887 | 0.78 | MMP2 (0.75) | MMP1MMP3MMP2MMP9ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258289-A4 | PEPTIDE ANALOGS | — | 1991-01-02 | — | — | EP | disclosed |
| EP-0258289-A1 | PEPTIDE ANALOGS | ABBOTT LABORATORIES (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004349-A1 | PEPTIDE ANALOGS | DELLARIA JOSEPH | 1987-07-30 | — | — | WO | disclosed |