Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829758 | 0.91 | SMN1; SMN2 (0.51) | RAB9AGAAKDM4ENPC1POLB | |
| SCHEMBL9833487 | 0.91 | ALDH1A1 (0.49) | RAB9AGAAKDM4ETBK1NPC1 | |
| SCHEMBL9830151 | 0.89 | MAPT (0.46) | RAB9AKDM4ENPC1SMN1; SMN2MAPT | |
| SCHEMBL9832334 | 0.84 | MAPT (0.38) | RAB9AKDM4ENPC1POLBSMN1; SMN2 | |
| SCHEMBL9830797 | 0.83 | RAB9A (0.39) | RAB9AGAAKDM4EIKBKETBK1 | |
| SCHEMBL9829923 | 0.82 | MAPT (0.43) | KDM4EPOLBSMN1; SMN2MAPTTP53 | |
| SCHEMBL9831169 | 0.82 | RAB9A (0.36) | RAB9AGAAKDM4EIKBKETBK1 | |
| SCHEMBL9829547 | 0.81 | SMN1; SMN2 (0.48) | RAB9AKDM4ENPC1POLBSMN1; SMN2 | |
| SCHEMBL9830723 | 0.80 | MAPT (0.41) | RAB9AGAAKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL9829826 | 0.80 | RAB9A (0.49) | RAB9AGAAKDM4ENPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |