Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832334 | 0.87 | MAPT (0.38) | MAPTLMNASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL9830151 | 0.83 | MAPT (0.46) | MAPTLMNASMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL9830916 | 0.82 | RAB9A (0.45) | MAPTLMNASMN1; SMN2HPGDTP53 | |
| SCHEMBL9829547 | 0.82 | SMN1; SMN2 (0.48) | MAPTLMNASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL9832252 | 0.81 | MAPT (0.43) | MAPTLMNASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL9831306 | 0.81 | MAPT (0.49) | MAPTLMNASMN1; SMN2L3MBTL1HPGD | |
| SCHEMBL9833487 | 0.80 | ALDH1A1 (0.49) | MAPTLMNASMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL9829758 | 0.78 | SMN1; SMN2 (0.51) | MAPTLMNASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL9823391 | 0.72 | TLR7 (0.48) | MAPTALDH1A1HDAC3HDAC1HDAC7 | |
| SCHEMBL11296296 | 0.71 | ALDH1A1 (0.58) | MAPTLMNASMN1; SMN2L3MBTL1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |