Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829547 | 0.90 | SMN1; SMN2 (0.48) | MAPTPOLBKMT2AMEN1L3MBTL1 | |
| SCHEMBL9830151 | 0.89 | MAPT (0.46) | MAPTKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9829923 | 0.87 | MAPT (0.43) | MAPTPOLBKMT2AMEN1L3MBTL1 | |
| SCHEMBL9830916 | 0.84 | RAB9A (0.45) | MAPTPOLBKDM4EALDH1A1HPGD | |
| SCHEMBL9833487 | 0.82 | ALDH1A1 (0.49) | MAPTPOLBKMT2AMEN1KDM4E | |
| SCHEMBL9829467 | 0.81 | ROCK1 (0.42) | MAPTPOLBKMT2AMEN1ROCK1 | |
| SCHEMBL9831900 | 0.80 | CYP1A1 (0.45) | MAPTROCK1TP53ADORA3 | |
| SCHEMBL9829758 | 0.80 | SMN1; SMN2 (0.51) | MAPTPOLBKMT2AMEN1KDM4E | |
| SCHEMBL9830211 | 0.74 | KDM4E (0.46) | MAPTPOLBKMT2AMEN1KDM4E | |
| SCHEMBL9832312 | 0.72 | ROCK1 (0.51) | MAPTPOLBKMT2AMEN1ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254856-B1 | PYRIDINETHANOL AMINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-04 | — | — | EP | disclosed |
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |