Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830916 | 0.91 | RAB9A (0.45) | ALDH1A1HPGDNPSR1SMN1; SMN2MAPT | |
| SCHEMBL9829758 | 0.88 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2MAPTGAANPC1 | |
| SCHEMBL9830151 | 0.86 | MAPT (0.46) | ALDH1A1SMN1; SMN2MAPTNPC1KDM4E | |
| SCHEMBL9829547 | 0.85 | SMN1; SMN2 (0.48) | ALDH1A1HPGDSMN1; SMN2MAPTNPC1 | |
| SCHEMBL9832334 | 0.82 | MAPT (0.38) | ALDH1A1HPGDSMN1; SMN2MAPTNPC1 | |
| SCHEMBL9829749 | 0.81 | DDX3X (0.44) | ALDH1A1HPGDSMN1; SMN2MAPTGAA | |
| SCHEMBL9829923 | 0.80 | MAPT (0.43) | ALDH1A1HPGDSMN1; SMN2MAPTKDM4E | |
| SCHEMBL9830803 | 0.79 | ALDH1A1 (0.62) | ALDH1A1HPGDNPSR1SMN1; SMN2MAPT | |
| SCHEMBL9830880 | 0.77 | CDK5 (0.52) | ALDH1A1HPGDNPSR1SMN1; SMN2MAPT | |
| SCHEMBL9832335 | 0.76 | KMT2A (0.62) | ALDH1A1HPGDNPSR1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |