Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 6/20 | 0.72 |
| ▸ | ACE | P12821 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CTSL | P07711 | 4/20 | 0.60 |
| ▸ | CTSS | P25774 | 2/20 | 0.60 |
| ▸ | CTSK | P43235 | 2/20 | 0.60 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.58 |
| ▸ | CTSV | O60911 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4177752 | 0.92 | GPR132 (0.65) | CTSBACEL3MBTL1CTSLCTSS | |
| SCHEMBL4798353 | 0.92 | GPR132 (0.65) | CTSBACEL3MBTL1CTSLCTSS | |
| SCHEMBL9829121 | 0.90 | CTSB (0.60) | CTSBACEL3MBTL1CTSLCTSS | |
| SCHEMBL28068999 | 0.87 | L3MBTL1 (0.56) | CTSBACEL3MBTL1CTSLCTSS | |
| SCHEMBL23279720 | 0.86 | CTSL (0.57) | CTSBACEL3MBTL1CTSLCTSS | |
| SCHEMBL23279723 | 0.86 | CTSL (0.57) | CTSBACEL3MBTL1CTSLCTSS | |
| SCHEMBL9829507 | 0.85 | CTSB (0.55) | CTSBACEL3MBTL1CTSLCTSS | |
| SCHEMBL111236 | 0.85 | ACE (0.76) | ACEL3MBTL1CTSLCTSSCTSK | |
| SCHEMBL528464 | 0.85 | ACE (0.76) | ACEL3MBTL1CTSLCTSSCTSK | |
| SCHEMBL111235 | 0.85 | ACE (0.76) | ACEL3MBTL1CTSLCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0226304-B1 | COMPOSITION CONTAINING A PENEM OR CARBAPENEM ANTIBIOTIC | SANKYO COMPANY LIMITED (JP) | 1991-08-28 | — | — | EP | disclosed |
| US-4757066-A | Reduces renal toxicity | SANKYO COMPANY LIMITED (JP) | 1988-07-12 | — | — | US | disclosed |
| EP-0226304-A1 | Composition containing a penem or carbapenem antibiotic | SANKYO COMPANY LIMITED (JP) | 1987-06-24 | — | — | EP | disclosed |