Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 1/20 | 0.58 |
| ▸ | MPL | P40238 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 3/20 | 0.49 |
| ▸ | USP8 | P40818 | 3/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | MRE11 | P49959 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829907 | 0.85 | LMNA (0.59) | GSTO1MPLCSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL9831892 | 0.85 | ABL1 (0.60) | GSTO1MPLMAPTMAPK1NPC1 | |
| SCHEMBL9832583 | 0.85 | LMNA (0.57) | GSTO1PARP1KDM4EMAPTMAPK1 | |
| SCHEMBL9829808 | 0.85 | RAB9A (0.58) | GSTO1PARP1MAPTMAPK1NPC1 | |
| SCHEMBL9829242 | 0.82 | ADORA3 (0.60) | GSTO1KDM4EMAPTMAPK1NPC1 | |
| SCHEMBL9831484 | 0.81 | MEN1 (0.64) | SIRT5MAPTNPC1RAB9ALMNA | |
| SCHEMBL9829872 | 0.80 | RAB9A (0.62) | GSTO1CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL9829548 | 0.80 | MEN1 (0.59) | MPLKDM4EMAPTNPC1RAB9A | |
| SCHEMBL9831311 | 0.79 | LMNA (0.60) | PARP1KDM4EMAPTMAPK1NPC1 | |
| SCHEMBL9831525 | 0.78 | NPC1 (0.60) | USP2KDM4EMAPTMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |