Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031442 | 0.92 | KDM4E (0.56) | KDM4ELMNAALDH1A1HSD17B10USP2 | |
| SCHEMBL8106730 | 0.89 | KDM4E (0.86) | KDM4ELMNAALDH1A1HSD17B10USP2 | |
| SCHEMBL9831380 | 0.89 | KDM4E (0.86) | KDM4ELMNAALDH1A1HSD17B10USP2 | |
| SCHEMBL3775215 | 0.84 | KDM4E (0.62) | KDM4ELMNAALDH1A1HSD17B10USP2 | |
| SCHEMBL9033301 | 0.79 | KDM4E (0.55) | KDM4ELMNAALDH1A1HSD17B10USP2 | |
| SCHEMBL432202 | 0.79 | KDM4E (0.66) | KDM4ELMNAALDH1A1HSD17B10USP2 | |
| SCHEMBL3503405 | 0.78 | KDM4E (1.00) | KDM4ELMNAALDH1A1HSD17B10USP2 | |
| SCHEMBL5359112 | 0.78 | GAA (0.59) | KDM4ELMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL1664197 | 0.78 | ALDH1A1 (0.65) | KDM4ELMNAALDH1A1HSD17B10TSHR | |
| SCHEMBL7378737 | 0.77 | KDM4E (0.45) | KDM4ELMNAALDH1A1HSD17B10USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023077218-A1 | PHOTOCATALYSTS, PREPARATION AND USE THEREOF | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY (CA) | 2023-05-11 | — | — | WO | disclosed |
| US-9657029-B2 | Method of preparing oxymorphone | SIEGFRIED GENERICS INTERNATIONAL AG (CH) | 2017-05-23 | — | — | US | disclosed |
| US-20150133484-A1 | METHOD OF PREPARING OXYMORPHONE | SIEGFRIED GENERICS INTERNATIONAL AG (CH) | 2015-05-14 | — | — | US | disclosed |
| EP-0253092-B1 | 1,4-DIHYDROPYRIDINES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS ANTITHROMBOTIC DRUGS | ALTER, S.A. (ES) | 1991-09-25 | — | — | EP | disclosed |
| US-4782069-A | INHIBITION OF PLATELET ACTIVATION | ALTER, S.A. (ES) | 1988-11-01 | — | — | US | disclosed |
| EP-0253092-A1 | 1,4-Dihydropyridines, processes for their preparation and their use as antithrombotic drugs | ALTER, S.A. (ES) | 1988-01-20 | — | — | EP | disclosed |
| US-4317768-A | A PHENYL DIESTER OF 3,5-DICARBOXY-1,4-DIHYDROPYRIDINE | LABAZ (FR) | 1982-03-02 | — | — | US | disclosed |
| US-4239893-A | STABILIZERS FOR VINYL RESINS | LABAZ (FR) | 1980-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150133484-A1 | METHOD OF PREPARING OXYMORPHONE | OPRK1, OPRD1, OGFR | KDM4E 4388/4885LMNA 3214/4885ALDH1A1 1182/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.