Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835029 | 0.83 | MAOB (0.39) | BRPF1CREBBPMAOB | |
| SCHEMBL9831075 | 0.82 | KDM4E (0.40) | — | |
| SCHEMBL9831475 | 0.78 | IDO1 (0.31) | MAOB | |
| SCHEMBL9831375 | 0.75 | KDM4E (0.41) | — | |
| SCHEMBL9835978 | 0.75 | PGR (0.43) | BRPF1CREBBP | |
| SCHEMBL9834483 | 0.74 | IDO1 (0.35) | BRPF1CREBBP | |
| SCHEMBL9834649 | 0.70 | ALDH1A1 (0.45) | BRPF1CREBBP | |
| SCHEMBL9833431 | 0.70 | CHRNB2 (0.40) | — | |
| SCHEMBL9831495 | 0.70 | CYP1A2 (0.37) | — | |
| SCHEMBL9833951 | 0.70 | CYP1A2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0214592-B1 | PYRROLOBENZIMIDAZOLES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS CONTAINING THESE PRODUCTS | Roche Diagnostics GmbH (DE) | 1991-08-14 | — | — | EP | disclosed |
| US-4730003-A | Tricyclic compounds for treating heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1988-03-08 | — | — | US | disclosed |
| EP-0214592-A2 | Pyrrolobenzimidazoles, process for their preparation and medicaments containing these products | Roche Diagnostics GmbH (DE) | 1987-03-18 | — | — | EP | disclosed |