Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830987 | 0.91 | GAA (0.54) | ALDH1A1HPGDNPSR1MAPTSMN1; SMN2 | |
| SCHEMBL9832642 | 0.88 | SMN1; SMN2 (0.64) | ALDH1A1HPGDNPSR1MAPTSMN1; SMN2 | |
| SCHEMBL9831938 | 0.87 | PPARA (0.49) | ALDH1A1HPGDNPSR1MAPTSMN1; SMN2 | |
| SCHEMBL9832312 | 0.86 | ROCK1 (0.51) | ALDH1A1HPGDNPSR1MAPTSMN1; SMN2 | |
| SCHEMBL9829467 | 0.83 | ROCK1 (0.42) | ALDH1A1HPGDNPSR1MAPTSMN1; SMN2 | |
| SCHEMBL9831974 | 0.81 | DDX3X (0.44) | ALDH1A1HPGDNPSR1MAPTSMN1; SMN2 | |
| SCHEMBL9832252 | 0.80 | MAPT (0.43) | ALDH1A1HPGDNPSR1MAPTSMN1; SMN2 | |
| SCHEMBL9833487 | 0.79 | ALDH1A1 (0.49) | ALDH1A1HPGDNPSR1MAPTSMN1; SMN2 | |
| SCHEMBL13407796 | 0.78 | ALDH1A1 (1.00) | ALDH1A1HPGDNPSR1MAPTSMN1; SMN2 | |
| SCHEMBL9833422 | 0.77 | ALOX5 (0.50) | ALDH1A1HPGDNPSR1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |