Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.64 |
| ▸ | MAPT | P10636 | 8/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | XDH | P47989 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830987 | 0.91 | GAA (0.54) | SMN1; SMN2MAPTGAARAB9ANPC1 | |
| SCHEMBL9830803 | 0.88 | ALDH1A1 (0.62) | SMN1; SMN2MAPTGAARAB9ANPC1 | |
| SCHEMBL9831938 | 0.88 | PPARA (0.49) | SMN1; SMN2MAPTGAARAB9ANPC1 | |
| SCHEMBL9829467 | 0.81 | ROCK1 (0.42) | SMN1; SMN2MAPTGAANPC1POLB | |
| SCHEMBL9832312 | 0.80 | ROCK1 (0.51) | SMN1; SMN2MAPTGAARAB9ANPC1 | |
| SCHEMBL9829758 | 0.80 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTGAARAB9ANPC1 | |
| SCHEMBL9832252 | 0.78 | MAPT (0.43) | SMN1; SMN2MAPTPOLBKDM4EMEN1 | |
| SCHEMBL9823541 | 0.78 | RAB9A (0.61) | SMN1; SMN2MAPTGAARAB9ANPC1 | |
| SCHEMBL14800165 | 0.76 | GAA (1.00) | SMN1; SMN2MAPTGAARAB9ANPC1 | |
| SCHEMBL9831974 | 0.75 | DDX3X (0.44) | SMN1; SMN2MAPTGAARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |