Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | XDH | P47989 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832642 | 0.91 | SMN1; SMN2 (0.64) | GAARAB9AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL9830803 | 0.91 | ALDH1A1 (0.62) | GAARAB9ASMN1; SMN2MAPTPOLB | |
| SCHEMBL9831938 | 0.90 | PPARA (0.49) | GAARAB9AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL9829467 | 0.85 | ROCK1 (0.42) | GAASMN1; SMN2MAPTPOLBALDH1A1 | |
| SCHEMBL9823368 | 0.83 | IKBKE (0.45) | GAARAB9AKDM4EMAPTPOLB | |
| SCHEMBL9832252 | 0.82 | MAPT (0.43) | KDM4ESMN1; SMN2MAPTPOLBALDH1A1 | |
| SCHEMBL9832312 | 0.82 | ROCK1 (0.51) | GAARAB9AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL9823324 | 0.81 | TBK1 (0.45) | GAARAB9AKDM4EPOLBALDH1A1 | |
| SCHEMBL9830916 | 0.79 | RAB9A (0.45) | GAARAB9AKDM4ESMN1; SMN2MAPT | |
| SCHEMBL9823799 | 0.79 | RAB9A (0.61) | GAARAB9AMAPTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321115-B1 | CARBOXAMIDE DERIVATIVES HAVING TETRAZOLE AND THIAZOLE RINGS AND THEIR USE | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-14 | — | — | EP | disclosed |
| US-4946855-A | ANTIALLERGIC | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1990-08-07 | — | — | US | disclosed |
| EP-0321115-A1 | Carboxamide derivatives having tetrazole and thiazole rings and their use | SAWAI PHARMACEUTICAL CO., LTD. (JP) | 1989-06-21 | — | — | EP | disclosed |