Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9829970 | 0.93 | ALDH1A1 (0.35) | DRD2DRD3 | |
| SCHEMBL10408223 | 0.91 | ALDH1A1 (0.37) | DRD2DRD3 | |
| SCHEMBL9830062 | 0.69 | ALDH1A1 (0.35) | DRD2DRD3 | |
| SCHEMBL9829972 | 0.67 | DRD2 (0.36) | DRD2DRD3 | |
| SCHEMBL10407364 | 0.66 | CHRM5 (0.43) | — | |
| SCHEMBL9830229 | 0.65 | ALDH1A1 (0.40) | DRD2DRD3 | |
| SCHEMBL9830255 | 0.63 | DRD2 (0.39) | DRD2DRD3 | |
| SCHEMBL2786474 | 0.63 | ALDH1A1 (0.46) | DRD2DRD3 | |
| SCHEMBL19684425 | 0.63 | L3MBTL3 (0.31) | — | |
| SCHEMBL9831065 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449989-A1 | 6,7 DIHYDROPYRROLO 3,4-c] PYRIDO 2,3-d] PYRIMIDINE DERIVATIVES | Sloan-Kettering Institute For Cancer Research (US) | 1991-10-09 | — | — | EP | claimed |
| WO-1990007496-A1 | 6,7 DIHYDROPYRROLO[3,4-c] PYRIDO[2,3-d] PYRIMIDINE DERIVATIVES | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-07-12 | — | — | WO | claimed |
| US-4925939-A | 6,7-dihydropyrrol[3,4-c]pyrido[2,3-d]pyrimidine derivatives | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-05-15 | — | — | US | disclosed |