Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 11/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.32 |
| ▸ | CHUK | O15111 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091957 | 0.84 | LMNA (0.43) | TDP1ALDH1A1HSD17B10 | |
| SCHEMBL9833339 | 0.78 | TSHR (0.48) | TDP1PTGS2PTGS1CA12CA2 | |
| SCHEMBL5891023 | 0.77 | ALDH1A1 (0.60) | TDP1ALDH1A1HSD17B10CA12CA2 | |
| SCHEMBL150162 | 0.77 | ALDH1A1 (0.60) | TDP1ALDH1A1HSD17B10CA12CA2 | |
| Water SCHEMBL7024182 | 0.74 | ALDH1A1 (0.57) | TDP1ALDH1A1HSD17B10CA12CA2 | |
| SCHEMBL5892101 | 0.74 | L3MBTL1 (0.46) | TDP1ALDH1A1HSD17B10 | |
| SCHEMBL651902 | 0.74 | ALDH1A1 (0.71) | TDP1ALDH1A1HSD17B10CA12CA2 | |
| SCHEMBL771038 | 0.73 | KDM4E (0.46) | TDP1ALDH1A1HSD17B10 | |
| SCHEMBL2799691 | 0.71 | LMNA (0.46) | — | |
| SCHEMBL5892108 | 0.71 | ALDH1A1 (0.41) | TDP1ALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224445-B1 | PYRROLO-PYRROLE PIGMENT PREPARATIONS, THEIR PREPARATION PROCESS AND THEIR USE | CIBA-GEIGY AG (CH) | 1991-09-04 | — | — | EP | disclosed |
| US-4914211-A | MIXTURE OF PYRROLOPYRROLES; COLORING HIGH MOLECULAR WEIGHT ORGANIC MATERIAL | CIBA-GEIGY CORPORATION (US) | 1990-04-03 | — | — | US | disclosed |
| US-4791204-A | FOR COLORING POLYMERS | CIBA-GEIGY CORPORATION (US) | 1988-12-13 | — | — | US | disclosed |