Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 2/20 | 0.39 |
| ▸ | CLCN2 | P51788 | 4/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | FABP2 | P12104 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9830328 | 0.90 | MAPT (0.35) | ACLYLMNAALDH1A1L3MBTL1PTGS2 | |
| SCHEMBL9832689 | 0.89 | ACLY (0.39) | ACLYEGFRMEN1KMT2ALMNA | |
| SCHEMBL9833895 | 0.88 | ACLY (0.41) | ACLYEGFRMEN1KMT2ALMNA | |
| SCHEMBL9832056 | 0.87 | METTL3 (0.38) | LMNAALDH1A1MAPK1METTL3 | |
| SCHEMBL9831781 | 0.86 | MAPT (0.37) | ACLYLMNAALDH1A1L3MBTL1 | |
| SCHEMBL9830400 | 0.85 | ALDH1A1 (0.36) | CLCN2LMNAALDH1A1 | |
| SCHEMBL9833689 | 0.83 | ACLY (0.36) | ACLYEGFRMEN1KMT2AALDH1A1 | |
| SCHEMBL9832673 | 0.82 | TSHR (0.50) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL8358915 | 0.82 | HSD11B1 (0.40) | ALDH1A1L3MBTL1 | |
| SCHEMBL9833348 | 0.82 | ACLY (0.35) | ACLYEGFRALDH1A1SORT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142152-B1 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1991-03-20 | — | — | EP | claimed |