Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | ATP4A | P20648 | 1/20 | 0.43 |
| ▸ | ATP4B | P51164 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4898749 | 0.90 | L3MBTL1 (0.53) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL5583648 | 0.87 | BCHE (0.50) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL4140684 | 0.87 | ABCB1 (0.53) | L3MBTL1MAPTMAPK1TDP1HTT | |
| SCHEMBL16356781 | 0.81 | L3MBTL1 (0.65) | L3MBTL1MAPTMAPK1TDP1STAT3 | |
| SCHEMBL4684239 | 0.81 | MGAM (0.44) | L3MBTL1MAPTMAPK1TDP1SMN1; SMN2 | |
| SCHEMBL17912878 | 0.79 | MAPT (0.66) | L3MBTL1MAPTMAPK1TDP1HTR1A | |
| SCHEMBL4681700 | 0.79 | RXRA (0.50) | SMN1; SMN2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL4688019 | 0.79 | HTR1A (0.43) | L3MBTL1MAPTMAPK1TDP1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10373109 | 0.79 | MAPT (0.41) | L3MBTL1MAPTMAPK1TDP1LTA4H | |
| SCHEMBL31517959 | 0.79 | L3MBTL1 (0.51) | L3MBTL1MAPTMAPK1TDP1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973906-A1 | HYDROXYDIHYDROPYRIDOPY RAZINE-1,8-DIONES AND METHODS FOR INHIBITING HIV INTEGRASE | Virochem Pharma Inc. (CA) | 2008-10-01 | — | — | EP | disclosed |
| WO-2006066414-A1 | HYDROXYDIHYDROPYRIDOPY RAZINE-1,8-DIONES AND METHODS FOR INHIBITING HIV INTEGRASE | VIROCHEM PHARMA INC. (CA) | 2006-06-29 | — | — | WO | disclosed |
| US-5723450-A | Substituted pyridines, their preparation, and their use as pesticides and fungicides | HOECHST SCHERING AGREVO GMBH (DE) | 1998-03-03 | — | — | US | disclosed |