Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 4/20 | 0.55 |
| ▸ | ANPEP | P15144 | 3/20 | 0.55 |
| ▸ | DNPEP | Q9ULA0 | 3/20 | 0.55 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.55 |
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | REN | P00797 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | KDM4A | O75164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5184565 | 0.78 | POLB (0.52) | LAP3ANPEPDNPEPRNPEPPOLB | |
| SCHEMBL9831068 | 0.77 | BACE1 (0.49) | — | |
| SCHEMBL7589901 | 0.76 | LAP3 (0.70) | LAP3ANPEPDNPEPRNPEPREN | |
| SCHEMBL7679505 | 0.76 | LAP3 (0.70) | LAP3ANPEPDNPEPRNPEPREN | |
| SCHEMBL6435664 | 0.73 | CNR1 (0.75) | LAP3ANPEPDNPEPRNPEPCNR1 | |
| SCHEMBL12381969 | 0.73 | CTSK (0.56) | CTSSCTSKPOLBCTSLCNR1 | |
| SCHEMBL7666024 | 0.73 | CNR1 (0.60) | LAP3ANPEPDNPEPRNPEPCNR1 | |
| SCHEMBL27684530 | 0.73 | POLB (0.74) | ANPEPCTSSCTSKPOLBCTSL | |
| SCHEMBL7319572 | 0.73 | CNR1 (0.60) | LAP3ANPEPDNPEPRNPEPCNR1 | |
| SCHEMBL9833327 | 0.72 | ALDH1A1 (0.54) | LAP3ANPEPDNPEPRNPEPREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0258289-A4 | PEPTIDE ANALOGS | — | 1991-01-02 | — | — | EP | disclosed |
| EP-0258289-A1 | PEPTIDE ANALOGS | ABBOTT LABORATORIES (US) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987004349-A1 | PEPTIDE ANALOGS | DELLARIA JOSEPH | 1987-07-30 | — | — | WO | disclosed |