Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836586 | 0.88 | RAB9A (0.35) | RAB9AMEN1KMT2ATBXAS1ALDH1A1 | |
| SCHEMBL9836067 | 0.80 | TBXAS1 (0.50) | RAB9AMEN1KMT2ATBXAS1ALDH1A1 | |
| SCHEMBL9870926 | 0.78 | RAB9A (0.43) | RAB9AMEN1KMT2ATBXAS1ALDH1A1 | |
| SCHEMBL9834147 | 0.78 | TBXAS1 (0.33) | TBXAS1 | |
| SCHEMBL9835750 | 0.76 | DRD2 (0.49) | ALDH1A1KDM4E | |
| SCHEMBL11531913 | 0.68 | RAB9A (0.37) | RAB9AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9835043 | 0.68 | TBXAS1 (0.52) | RAB9AMEN1KMT2ATBXAS1ALDH1A1 | |
| SCHEMBL5635575 | 0.66 | IDO1 (0.54) | ALDH1A1KDM4E | |
| SCHEMBL9836834 | 0.66 | ALDH1A1 (0.44) | RAB9AMEN1KMT2ATBXAS1ALDH1A1 | |
| SCHEMBL3235870 | 0.65 | KDM4E (0.40) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |