SCHEMBL9834147

SCHEMBL9834147

CS(=O)(=O)OCC1CCc2cc(C=O)sc2C1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9836586 0.90 RAB9A (0.35) TBXAS1
SCHEMBL9835650 0.79 TBXAS1 (0.52) TBXAS1
SCHEMBL9834608 0.78 RAB9A (0.36) TBXAS1
SCHEMBL9837267 0.77 TBXAS1 (0.43) TBXAS1
SCHEMBL9835187 0.75 DRD2 (0.50)
SCHEMBL10827763 0.70 CYP19A1 (0.44)
SCHEMBL9837021 0.69 DRD2 (0.51)
SCHEMBL11531913 0.69 RAB9A (0.37)
SCHEMBL9835043 0.69 TBXAS1 (0.52) TBXAS1
SCHEMBL9837204 0.69 TBXAS1 (0.38) TBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0240107-B1 THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE Sankyo Company Limited (JP) 1991-08-21 EP disclosed
US-5021444-A Anticoagulants SANKYO COMPANY LIMITED (JP) 1991-06-04 US disclosed
US-4847272-A ANTICOAGULANTS SANKYO COMPANY LIMITED (JP) 1989-07-11 US disclosed
EP-0240107-A1 Thianaphthene derivatives, their production and use Sankyo Company Limited (JP) 1987-10-07 EP disclosed