Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLCN2 | P51788 | 4/20 | 0.35 |
| ▸ | ACLY | P53396 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | FABP2 | P12104 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9831382 | 0.90 | MAPT (0.36) | LMNAMAPK1PTGS2MAPT | |
| SCHEMBL9832427 | 0.90 | ACLY (0.34) | CLCN2ACLYMEN1KMT2ALMNA | |
| SCHEMBL9832083 | 0.88 | ACLY (0.39) | CLCN2ACLYMEN1KMT2ALMNA | |
| SCHEMBL9831367 | 0.88 | IKBKB (0.38) | MEN1KMT2ALMNAMAPK1METTL3 | |
| SCHEMBL9831829 | 0.87 | MAPT (0.35) | MAPT | |
| SCHEMBL9832446 | 0.86 | ALDH1A1 (0.33) | CLCN2MEN1KMT2ALMNA | |
| SCHEMBL10525925 | 0.84 | ACLY (0.32) | ACLYMAPK1 | |
| SCHEMBL9833898 | 0.83 | METAP2 (0.33) | ACLYMEN1KMT2AHSD17B10 | |
| SCHEMBL9830515 | 0.82 | SLC40A1 (0.35) | KMT2ACCR4 | |
| SCHEMBL9834365 | 0.82 | METAP2 (0.33) | ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142152-B1 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1991-03-20 | — | — | EP | claimed |