Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 3/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9832427 | 0.90 | ACLY (0.34) | METAP2ACLYMEN1KMT2AHSD17B10 | |
| SCHEMBL9830248 | 0.90 | MAPK14 (0.34) | ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9834365 | 0.88 | METAP2 (0.33) | METAP2ACLYPDE2AALDH1A1PTGER4 | |
| SCHEMBL9833863 | 0.87 | ACLY (0.46) | METAP2ACLYPDE2AALDH1A1KDM4E | |
| SCHEMBL9832765 | 0.87 | LMNA (0.39) | ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9832670 | 0.86 | CA12 (0.31) | PDE2A | |
| SCHEMBL9831767 | 0.85 | SLC40A1 (0.31) | METAP2 | |
| SCHEMBL9834743 | 0.83 | CLCN2 (0.35) | ACLYMEN1KMT2AHSD17B10 | |
| SCHEMBL9832072 | 0.83 | ACLY (0.35) | METAP2ACLYALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9832083 | 0.83 | ACLY (0.39) | METAP2ACLYMEN1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0142152-B1 | Novel substituted 1,2,4-triazolo- [1,5-a] pyrimidine-2-sulfonamides and compositions and methods of controlling undesired vegetation and suppressing the nitrification of ammonium nitrogen in soil | THE DOW CHEMICAL COMPANY (US) | 1991-03-20 | — | — | EP | claimed |