SCHEMBL9835622

SCHEMBL9835622

CS(=O)(=O)Nc1ccc(N[C]=O)cc1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.56
ALDH1A1 P00352 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
LMNA P02545 2/20 0.55
KDM4E B2RXH2 1/20 0.55
HPGD P15428 1/20 0.55
HTT P42858 1/20 0.55
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
KIF11 P52732 3/20 0.52
NR3C2 P08235 5/20 0.52
PGR P06401 1/20 0.48
MAPT P10636 1/20 0.47
CYP2C9 P11712 1/20 0.47
GAA P10253 1/20 0.44
MAPK1 P28482 1/20 0.44
PTGS2 P35354 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12054668 0.83 KEAP1 (0.75) KEAP1ALDH1A1SMN1; SMN2LMNAKDM4E
SCHEMBL8390036 0.80 KEAP1 (0.53) KEAP1ALDH1A1SMN1; SMN2HTTKIF11
SCHEMBL82733 0.79 CA1 (0.64) KEAP1ALDH1A1SMN1; SMN2LMNAKDM4E
SCHEMBL6696494 0.78 KEAP1 (0.56) KEAP1ALDH1A1SMN1; SMN2LMNAKDM4E
SCHEMBL7771139 0.78 ENPP2 (0.46) SMN1; SMN2CA12CA1CA2CA9
SCHEMBL7789704 0.78 MEN1 (0.32) LMNA
SCHEMBL11562750 0.77 CA1 (0.61) KEAP1ALDH1A1SMN1; SMN2LMNAKDM4E
SCHEMBL31041151 0.77 KIF11 (0.79) KEAP1ALDH1A1SMN1; SMN2LMNAKDM4E
SCHEMBL6406076 0.76 NR3C2 (0.59) KEAP1ALDH1A1SMN1; SMN2LMNAKDM4E
SCHEMBL21836010 0.75 ALDH1A1 (0.68) ALDH1A1SMN1; SMN2LMNAKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0215124-B1 SILVER HALIDE PHOTOGRAPHIC PHOTO-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1991-09-04 EP disclosed
US-4925782-A Silver halide photographic light-sensitive element containing water soluble dye compounds FUJI PHOTO FILM CO., LTD. (JP) 1990-05-15 US disclosed
US-4879204-A HIGH CONTRAST FUJI PHOTO FILM CO., LTD. (JP) 1989-11-07 US disclosed
EP-0215124-A1 SILVER HALIDE PHOTOGRAPHIC PHOTO-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1987-03-25 EP disclosed