Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FOLR1 | P15328 | 1/20 | 0.33 |
| ▸ | GART | P22102 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837267 | 0.91 | TBXAS1 (0.43) | TBXAS1ALDH1A1KDM4EGLARAB9A | |
| SCHEMBL9835043 | 0.90 | TBXAS1 (0.52) | TBXAS1ALDH1A1DAORAB9ANPC1 | |
| SCHEMBL9836834 | 0.81 | ALDH1A1 (0.44) | TBXAS1ALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL9834147 | 0.79 | TBXAS1 (0.33) | TBXAS1 | |
| SCHEMBL9836067 | 0.79 | TBXAS1 (0.50) | TBXAS1ALDH1A1DAORAB9ANPC1 | |
| SCHEMBL7618716 | 0.78 | TBXAS1 (0.52) | TBXAS1ALDH1A1DAORAB9ANPC1 | |
| SCHEMBL9835187 | 0.74 | DRD2 (0.50) | KMT2A | |
| SCHEMBL1397374 | 0.73 | ALDH1A1 (0.56) | TBXAS1ALDH1A1DAOKDM4ERAB9A | |
| SCHEMBL9870926 | 0.70 | RAB9A (0.43) | TBXAS1ALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL3347584 | 0.70 | TBXAS1 (0.59) | TBXAS1ALDH1A1DAOKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |