SCHEMBL9835875

SCHEMBL9835875

C=C(C)C(OC(=O)Nc1ccc(F)c(OC(C)C)c1)C(=O)OCC(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.46
IDO1 P14902 1/20 0.39
TDO2 P48775 1/20 0.39
RORC P51449 1/20 0.38
KDM4E B2RXH2 2/20 0.37
CASP3 P42574 1/20 0.37
LMNA P02545 4/20 0.36
TSHR P16473 3/20 0.36
HTT P42858 2/20 0.36
MAPK1 P28482 1/20 0.36
ALOX15 P16050 2/20 0.36
HPGD P15428 1/20 0.36
KCNQ3 O43525 1/20 0.36
KCNQ2 O43526 1/20 0.36
DRD2 P14416 1/20 0.35
ADRA1D P25100 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRA1B P35368 1/20 0.35
GRM4 Q14833 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9837090 0.88 SMN1; SMN2 (0.46) SMN1; SMN2RORCKDM4ELMNATSHR
SCHEMBL9834578 0.81 SMN1; SMN2 (0.41) SMN1; SMN2IDO1TDO2CASP3LMNA
SCHEMBL9837098 0.80 SMN1; SMN2 (0.56) SMN1; SMN2KDM4ELMNATSHRHTT
SCHEMBL9836348 0.80 RORC (0.37) SMN1; SMN2RORCLMNATSHRMAPK1
SCHEMBL9836883 0.79 GRM4 (0.46) SMN1; SMN2IDO1TDO2TSHRHPGD
SCHEMBL9836705 0.78 IDO1 (0.41) SMN1; SMN2IDO1TDO2RORCKDM4E
SCHEMBL9835708 0.77 LMNA (0.52) SMN1; SMN2CASP3LMNATSHRHTT
SCHEMBL9836764 0.77 SMN1; SMN2 (0.39) SMN1; SMN2IDO1TDO2RORCKDM4E
SCHEMBL9836398 0.76 RORC (0.49) SMN1; SMN2RORCKDM4ELMNAHTT
SCHEMBL9836744 0.76 GAA (0.44) SMN1; SMN2RORCKDM4ELMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1027069-C Process for producing oxazolidinedione derivative SAGAMI CHEM RES (JP) 1994-12-21 CN disclosed
CN-1059718-A The weedicide that contains the  oxazolidinedione derivatives SAGAMI CHEM RES (JP) 1992-03-25 CN disclosed
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed
CN-86108416-A Oxazolidinedione derivative, process for producing the same, and herbicide containing the same 1987-07-29 CN disclosed