Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7712683 | 0.73 | TSHR (0.47) | ALDH1A1HPGDKDM4ETDP1L3MBTL1 | |
| SCHEMBL29433567 | 0.73 | TSHR (0.47) | ALDH1A1HPGDKDM4ETDP1L3MBTL1 | |
| SCHEMBL25060076 | 0.72 | MAPT (0.42) | ALDH1A1HPGDKDM4ETDP1MAPT | |
| SCHEMBL21474553 | 0.70 | TSHR (0.43) | ALDH1A1HPGDKDM4ETDP1L3MBTL1 | |
| SCHEMBL21474578 | 0.69 | ALOX15 (0.43) | ALDH1A1HPGDKDM4EPRKCZTSHR | |
| SCHEMBL15871033 | 0.68 | PNMT (0.33) | — | |
| SCHEMBL14761354 | 0.68 | ALDH1A1 (0.44) | ALDH1A1HPGDKDM4EL3MBTL1MAPT | |
| SCHEMBL6034342 | 0.67 | TSHR (0.42) | ALDH1A1KDM4ETDP1MAPTGAA | |
| SCHEMBL10708787 | 0.67 | KCNK3 (0.46) | ALDH1A1HPGDKDM4EMAPTGAA | |
| SCHEMBL22070685 | 0.66 | TLR8 (0.50) | ALDH1A1HPGDKDM4ETDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0240107-B1 | THIANAPHTHENE DERIVATIVES, THEIR PRODUCTION AND USE | Sankyo Company Limited (JP) | 1991-08-21 | — | — | EP | disclosed |
| US-5021444-A | Anticoagulants | SANKYO COMPANY LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4847272-A | ANTICOAGULANTS | SANKYO COMPANY LIMITED (JP) | 1989-07-11 | — | — | US | disclosed |
| EP-0240107-A1 | Thianaphthene derivatives, their production and use | Sankyo Company Limited (JP) | 1987-10-07 | — | — | EP | disclosed |