Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21474578 | 0.84 | ALOX15 (0.43) | TSHRPRKCZMEN1KMT2AHPGD | |
| SCHEMBL14761354 | 0.83 | ALDH1A1 (0.44) | PRKCZMAPTMEN1KMT2ACASP3 | |
| SCHEMBL22070685 | 0.81 | TLR8 (0.50) | TSHRMAPTMEN1KMT2AHPGD | |
| SCHEMBL29433567 | 0.81 | TSHR (0.47) | TSHRMAPTMEN1KMT2AHPGD | |
| SCHEMBL7712683 | 0.81 | TSHR (0.47) | TSHRMAPTMEN1KMT2AHPGD | |
| SCHEMBL8092437 | 0.81 | ADRA2A (0.43) | TSHRMAPK14MAPTMEN1KMT2A | |
| SCHEMBL7388942 | 0.79 | ALOX5 (0.43) | TSHRPRKCZMAPTMEN1KMT2A | |
| SCHEMBL10708787 | 0.77 | KCNK3 (0.46) | MAPTMEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL7714827 | 0.72 | TSHR (0.45) | TSHRMAPTMEN1KMT2ACASP3 | |
| SCHEMBL1031296 | 0.72 | NOTUM (0.36) | TSHRMAPK14KMT2AALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019199979-A1 | ANTIBACTERIAL COMPOUNDS | THE GENERAL HOSPITAL CORPORATION (US) | 2019-10-17 | — | — | WO | disclosed |