Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 2/20 | 0.67 |
| ▸ | CTSL | P07711 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.47 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4214475 | 0.87 | CRHBP (0.70) | CTSVCTSLMAPTCRHBPCRHR2 | |
| SCHEMBL4205393 | 0.87 | CRHBP (0.70) | CTSVCTSLMAPTCRHBPCRHR2 | |
| SCHEMBL9834480 | 0.87 | CRHBP (0.70) | CTSVCTSLMAPTCRHBPCRHR2 | |
| SCHEMBL9837846 | 0.86 | CTSV (0.56) | CTSVCTSLMAPTCRHBPCRHR2 | |
| SCHEMBL9838079 | 0.86 | MAPT (0.58) | CTSVCTSLMAPTCRHBPCRHR2 | |
| SCHEMBL7331118 | 0.81 | CTSV (1.00) | CTSVCTSLMAPTAKR1C3AKR1C2 | |
| SCHEMBL9837317 | 0.81 | ANO1 (0.57) | CTSVCTSLMAPTCRHBPCRHR2 | |
| SCHEMBL22720146 | 0.80 | CTSV (0.81) | CTSVCTSLMAPTAKR1C3AKR1C2 | |
| SCHEMBL17434401 | 0.80 | MAPT (0.70) | CTSVCTSLMAPTAKR1C3AKR1C2 | |
| SCHEMBL15003946 | 0.76 | ALDH1A1 (0.60) | MAPTKMT2AMEN1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994493-A | Treatment of cerebral edema | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN (DE) | 1991-02-19 | — | — | US | disclosed |