Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 2/20 | 0.56 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.53 |
| ▸ | ANO2 | Q9NQ90 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9835884 | 0.86 | CTSV (0.67) | CTSVCTSLANO1ANO2MAPT | |
| SCHEMBL9837317 | 0.83 | ANO1 (0.57) | CTSVCTSLANO1ANO2MAPT | |
| SCHEMBL4214475 | 0.82 | CRHBP (0.70) | CTSVCTSLANO1ANO2MAPT | |
| SCHEMBL9834480 | 0.82 | CRHBP (0.70) | CTSVCTSLANO1ANO2MAPT | |
| SCHEMBL4205393 | 0.82 | CRHBP (0.70) | CTSVCTSLANO1ANO2MAPT | |
| SCHEMBL9838079 | 0.81 | MAPT (0.58) | CTSVCTSLMAPTLMNAKMT2A | |
| SCHEMBL17434401 | 0.78 | MAPT (0.70) | CTSVCTSLMAPTSMN1; SMN2LMNA | |
| SCHEMBL1671926 | 0.76 | CTSV (0.60) | CTSVCTSLANO1ANO2MAPT | |
| SCHEMBL9837463 | 0.76 | MPO (0.56) | CTSVCTSLMAPTLMNAKMT2A | |
| SCHEMBL3022957 | 0.75 | MAPT (0.67) | CTSVCTSLANO1ANO2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4994493-A | Treatment of cerebral edema | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN (DE) | 1991-02-19 | — | — | US | disclosed |