Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 2/20 | 0.38 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12922764 | 0.90 | TYR (0.44) | MAPK1HIF1ATDP1CNR2SMN1; SMN2 | |
| SCHEMBL18805967 | 0.90 | TYR (0.44) | MAPK1HIF1ATDP1CNR2SMN1; SMN2 | |
| SCHEMBL197810 | 0.84 | ADRB2 (0.65) | ADRB2TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL16021748 | 0.84 | CHKA (0.46) | MAPK1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL23134953 | 0.83 | ADRB2 (0.43) | ADRB2TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL30720007 | 0.82 | ADRB2 (0.62) | ADRB2TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL4445207 | 0.82 | ADRB2 (0.62) | ADRB2TSHRMAPK1HIF1ATDP1 | |
| Hydrochloric Acid SCHEMBL28767407 | 0.82 | ADRB2 (0.62) | ADRB2TSHRMAPK1HIF1ATDP1 | |
| SCHEMBL666720 | 0.82 | LMNA (0.57) | TSHRMAPK1HIF1ATDP1CNR2 | |
| SCHEMBL12367721 | 0.81 | CHRNA7 (0.44) | TSHRTDP1CNR2LMNATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11124524-B2 | Diarylethene compounds and uses thereof | SOLUTIA CANADA INC. (US) | 2021-09-21 | — | — | US | disclosed |
| US-10663771-B2 | Optical filter with light source | SWITCH MATERIALS, INC. (CA) | 2020-05-26 | — | — | US | disclosed |
| US-20190346702-A1 | OPTICAL FILTER WITH LIGHT SOURCE | SWITCH MATERIALS, INC. (CA) | 2019-11-14 | — | — | US | disclosed |
| US-20190256526-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2019-08-22 | — | — | US | disclosed |
| US-10310300-B2 | Optical filter with light source | SWITCH MATERIALS, INC. (CA) | 2019-06-04 | — | — | US | disclosed |
| US-20180210240-A1 | OPTICAL FILTER WITH LIGHT SOURCE | SWITCH MATERIALS, INC. (CA) | 2018-07-26 | — | — | US | disclosed |
| US-20180210240-A1 | OPTICAL FILTER WITH LIGHT SOURCE | SWITCH MATERIALS, INC. (CA) | 2018-07-26 | — | — | US | disclosed |
| US-9910301-B2 | Switchable optical filter apparatus with light | SWITCH MATERIALS, INC. (CA) | 2018-03-06 | — | — | US | disclosed |
| US-20160083398-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2016-03-24 | — | — | US | disclosed |
| US-9227986-B2 | Diarylethene compounds and uses thereof | SWITCH MATERIALS, INC. (CA) | 2016-01-05 | — | — | US | disclosed |
| US-20150036204-A1 | OPTICAL FILTER WITH LIGHT SOURCE | SWITCH MATERIALS, INC. (CA) | 2015-02-05 | — | — | US | disclosed |
| US-20140256936-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | SWITCH MATERIALS, INC. (CA) | 2014-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256526-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | ADRB2 410/4885TSHR 797/4885MAPK1 2807/4885 |
| US-11124524-B2 | Diarylethene compounds and uses thereof | KCNH2, KCNH3, SCN2B | ADRB2 410/4885TSHR 797/4885MAPK1 2807/4885 |
| US-20140256936-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | ADRB2 410/4885TSHR 797/4885MAPK1 2807/4885 |
| US-20160083398-A1 | DIARYLETHENE COMPOUNDS AND USES THEREOF | KCNH2, KCNH3, SCN2B | ADRB2 410/4885TSHR 797/4885MAPK1 2807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.